ABSTRACT
Background: Type2 diabetes is characterized by a long asymptomatic period commonly to be diagnosed when complications appear. The risk factors associated with diabetes are age, hypertension, dyslipidemia, smoking, alcohol, obesity & others. The role of early detection and adequate treatment of diabetes and related complications patients and health services is the basis for present study.Methods: The present study was conducted at S.N. Medical College, Agra, India on 86 consecutive newly diagnosed cases of type 2 diabetes. All individuals aged ≥ 20 years of age, who were not known diabetic, presenting to medicine department were included in the study for the targeted and opportunistic screening duration of January 2011 to June 2012.Results: The prevalence rates of vascular complications in this study group were analyzed statistically. The findings are the mean age was 54.27±9.27 years. 72.09% of newly diagnosed type 2 diabetes patients were aged above 50 years. Maximum number of patients were overweight (37.20%) followed by obese (32.55%). Hypertension was present in 30.23%, prevalence of CAD was 9.30%, and none had evidence of PVD and Cerebrovascular disease.Conclusions: Macrovascular complications were present in 9.30% of asymptomatic newly diagnosed type 2 diabetes patients. In the study present study found that there was a significant association of these risk factors were identified and treated as early as possible to decrease the progression of vascular complications.
ABSTRACT
Aims:The study aims to estimate the lipid parameters among Plasmodium vivaxand mixed malaria (P.falciparum and P. vivax) infected patients. Study Design:This was a prospective observational and comparative study.Place and Duration of Study:The present study was undertaken in the Departments of Medicine and Biochemistry at A.J. Institute of Medical Sciences and Research (AJIMS), Mangaluru, Karnatakabetween Dec 2017 and May 2018.Methods:It was a prospective observational comparative study. A total of 100 patients (50 P. vivaxand 50 mixed malaria cases) were consecutively taken in the study. The lipid profiles of the cases were compared with that of100 healthy volunteers (control group). Data was collected and analysed. Results:Serum total cholesterol, High-Density Lipoprotein (HDL) and Low-Density Lipoprotein (LDL) levels were significantly low(p<0.001) in cases and serum Triglycerides (TG) andVery Low-Density Lipoprotein levels (VLDL) were higher in cases (p<0.001) than in control. There were no significant changes in mean serum lipids profiles between P. vivaxand Mixed Malaria groups. Conclusion:The derangement in lipid profiles in falciparum malaria was characteristic and specific for the disease. Characteristic changes were lower HDL, LDL and total cholesterol levels with higher TG and VLDL levels in comparison to control groups. These findings may be of diagnostic and prognostic value.